Supplementary Figure 4: Stereo views of tunicamycin bound to hGPT. | Nature Structural & Molecular Biology

Supplementary Figure 4: Stereo views of tunicamycin bound to hGPT.

From: GlcNAc-1-P-transferase–tunicamycin complex structure reveals basis for inhibition of N-glycosylation

Supplementary Figure 4

The canonical hGPT (Pro129) is shown at the top (3.1 Å resolution), while the His129 variant is shown below (2.95 Å resolution). Tunicamycin is denoted as magenta sticks. 2F o –F c omit density of tunicamycin is shown in blue mesh (contoured to 0.8 σ), while the F o –F c omit density of tunicamycin is shown in green mesh (contoured to 3 σ). Maps were carved 1.8 Å from the tunicamycin model.

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