Supplementary Figure 2: Loci showing expression changes and formation of new heterochromatin islands in wild-type cells grown at 18 °C are enriched in stress response genes.
From: Iron homeostasis regulates facultative heterochromatin assembly in adaptive genome control
(Left) Histogram showing the numbers of genes in broad categories with increased expression (fold change value ≥ 1 and P value < 0.05) or decreased expression (fold change value ≤ 1 and P value < 0.05) in wild-type cells grown at 18 °C relative to wild-type cells grown at 30 °C as determined by RNA-seq (n = 2 independent experiments per condition). Genes with increased expression are shown in red and genes with decreased expression are shown in blue. Statistical significance (right-hand, single-tailed P value of binomial distribution, n=6380 transcripts) of the number of genes with increased expression is listed on the right. (Right) List of categories for genes within heterochromatin islands in wild-type cells grown at 18 °C as determined by ChIP-chip. Statistical significance (P value) of the number of genes within 18 °C heterochromatin islands is listed for each category.
