Supplementary Figure 6: Binding assays of AngII and [Sar1, Ile8]-AngII for wild-type AT2R with or without Fab4A03.
From: Crystal structure of the human angiotensin II type 2 receptor bound to an angiotensin II analog
a,b, Specific binding assays of 125I-labeled [Sar1, Ile8]-AngII (a) and AngII (b) for wild-type AT2R with (square) or without (circle) Fab4A03. The corresponding Kd and Bmax values were calculated by fitting a non-linear curve. Each point represents the means ± s.d. of triplicate experiments. Vertical axes indicate relative specific binding values. [Sar1, Ile8]-AngII is abbreviated s-AngIl.
