Supplementary Figure 3: Crystal packing view, overall electron density map and electron density map of [Sar1, Ile8]-AngII.
From: Crystal structure of the human angiotensin II type 2 receptor bound to an angiotensin II analog
a, Crystal packing views parallel to the membrane layer. Each molecule is colored as follows: AT2R (green), BRIL (cyan), Fab4A03L (salmon) and Fab4A03H (yellow-orange). b, The electron density 2mFo–DFc map was calculated from the 3.2-Å resolution dataset contoured at 1.0σ. c, The omitted mFo–DFc electron density (blue mesh) contoured at 1.5σ (omit map), 3.0σ (omit map) and 3.0σ (Polder map, or improved omit map, implemented in the PHENIX software suite). AT2R is shown as a green cylindrical cartoon. [Sar1, Ile8]-AngII is shown as a licorice model with a yellow backbone, blue nitrogen atoms and red oxygen atoms. [Sar1, Ile8]-AngII is abbreviated s-AngIl.
