Supplementary Figure 6: The relationship of the adjacent to the HAT domain modules.
From: The ZZ domain of p300 mediates specificity of the adjacent HAT domain for histone H3
a, Superimposed 1H,15N HSQC spectra of p300 BD-RING-PHD collected upon titration with the indicated histone peptides. Spectra are color-coded according to the protein:peptide molar ratio. b, Superimposed 1H,15N HSQC spectra of p300 BD-RING-PHD collected upon titration with HAT or HAT-ZZ. Spectra are color-coded according to the protein:ligand molar ratio. c, Superimposed 1H,15N HSQC spectra of p300-ZZ (red) and HAT-ZZ (black).
