Supplementary Figure 2: XRN2, CARF and p32 levels are increased in melanoma.
From: SAMMSON fosters cancer cell fitness by concertedly enhancing mitochondrial and cytosolic translation
a, Western blot for XRN2, CARF and p32 in NHEM, in SK-MEL-28 WT or BRAFi resistant (SK-MEL-28-R) and in a panel of short-term melanoma cultures (MM-lines, with different mutational backgrounds and phenotype). b, SAMMSON and HRPT pulldown in native (−) and ultraviolet crosslinking (+) conditions (using two sets of 48 biotinylated probes recognizing mature transcripts, p) and western blotting in SK-MEL-28 cells. Representative image of three independent experiments. Uncropped gel images are shown in Supplementary Data Set 1.
