Supplementary Figure 4: Chromatin fractions are enriched for lncRNA and pre-mRNA (intron) structural information. | Nature Structural & Molecular Biology

Supplementary Figure 4: Chromatin fractions are enriched for lncRNA and pre-mRNA (intron) structural information.

From: RNA structure maps across mammalian cellular compartments

Supplementary Figure 4

a-b, Structural models of (a) Ribonuclease P RNA, and (b) Signal recognition particle (SRP) RNA. Models are generated from the ViennaRNA web service based on data from the RNASTRAND database. Nucleotides are colored with icSHAPE scores from the nucleoplasm fraction. c, Histograms of ratios of lncRNAs versus all transcripts in different cellular compartments for human and mouse. d, Histograms of ratios of the sequencing reads mapped to introns versus all transcripts in different cellular compartments for human and mouse. e-g, Violin plot of Gini index of icSHAPE data in exon versus in intron in (e) mRNAs from mES cells, (f) mRNAs from HEK293 cells depleted of RBP-binding sites (20nt) and (g) mRNAs from HEK293 cells depleted of RBP-binding sites (100nt).

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