Supplementary Figure 5: RNA structure plays a central role in connecting transcription, translation and RNA degradation.
From: RNA structure maps across mammalian cellular compartments
a-i, Kernel density estimation (KDE) plots (a,c,e,g), scatter plots (b,d,f,h), and scatter plots with a higher read depth cutoff (read depth =200) (i) of transcription rate versus 5’UTR RNA structure in chromatin, translational efficiency versus 5’UTR RNA structure in cytoplasm, RNA half-life versus full-length-transcript RNA structure in nucleoplasm, and RNA half-life versus RNA structure in cytoplasm. The two-tailed p-value was calculated by python package function scipy.stats.pearsonr. j-l, Scatter plots of transcription rate versus 5’UTR RNA structure in chromatin. Transcription rates are from published datasets: Min, I. M. et al. Genes & development. 25, 742–754, 2011 (j) and Tastemel, M. et al. Stem Cell Res. 25, 250–255, 2017 (k). translational efficiency versus 5’UTR RNA structure in cytoplasm (l). Translational efficiency data are from a published report (Yoshikawa, H. et al. eLife. 7, 2018).
