Supplementary Figure 1: The cXR-tXA model can reproduce up-regulation of Xist in differentiating mESCs.
From: A symmetric toggle switch explains the onset of random X inactivation in different mammals
Fraction of cells exhibiting mono-allelic (light grey) and bi-allelic Xist expression (dark grey) during differentiation of mESC line TX1072. Experimental data (circles) is shown together with a simulation using the parameter set that best explains the data. The number of cells analyzed is given on top. The data was pooled from 3 independent experiments.
