Supplementary Figure 3: Remodeler redundancy in nucleosome positioning. | Nature Structural & Molecular Biology

Supplementary Figure 3: Remodeler redundancy in nucleosome positioning.

From: Opposing chromatin remodelers control transcription initiation frequency and start site selection

Supplementary Figure 3

a, Nucleosome occupancy change upon depletion of RSC (left) or SWI-SNF (right) at sites bound by each remodeler and displaying varying binding signal (+, +/-, -) of the other one. b, Nucleosome occupancy change upon depletion of ISW2 at sites bound by this remodeler and displaying varying binding signal of INO80 (as in (a)). c, Nucleosome occupancy change upon depletion of INO80 at sites bound by this remodeler and displaying varying binding signal of ISW2 (as in (a)). d, Boxplot of INO80 binding signal at INO80-bound sites displaying varying binding signal of ISW2. In (a-d), asterisks indicate significant differences (p<0.05, Mann-Whitney test). e, Snapshot of a sample genomic region displaying nucleosome occupancy change upon depletion of ISW1, CHD1 or both remodelers simultaneously.

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