Supplementary Figure 4: Multiple concordant and opposing remodeler activities control promoter nucleosome occupancy.
From: Opposing chromatin remodelers control transcription initiation frequency and start site selection
a, Nucleosome occupancy change upon RSC depletion at sites bound by RSC (left) and change upon SWI-SNF depletion at sites bound by SWI-SNF (right). In both cases comparisons are made between sites co-bound by ISW2 (+) or not (-). Asterisk indicates significant difference (p<0.05, Mann-Whitney test). b, Nucleosome occupancy change upon INO80 depletion at sites bound by INO80 and co-bound by RSC and/or SWI-SNF or not, as indicated below. c, Average plots of nucleosome occupancy for all nucleosomes destabilized upon depletion of ISW2, comparing wild-type cells and cells depleted of RSC, ISW2, or both remodelers simultaneously. d, Average plots of nucleosome occupancy for all nucleosomes destabilized upon depletion of INO80, comparing for wild-type cells and cells depleted of RSC, INO80, or both remodelers simultaneously. e, Average plots of nucleosome occupancy for all nucleosomes stabilized upon depletion of RSC, comparing wild-type cells and cells depleted of RSC, RSC and ISW2, RSC and INO80, or all three remodelers simultaneously.
