Extended Data Fig. 4: Attachment of YFP had no effect on BiP functionality. | Nature Structural & Molecular Biology

Extended Data Fig. 4: Attachment of YFP had no effect on BiP functionality.

From: UPR proteins IRE1 and PERK switch BiP from chaperone to ER stress sensor

Extended Data Fig. 4

(a) ATPase activity of BiP and YFP tagged BiP. (b) Comparison of the rate of ATPase activity for BiP and YFP- tagged BiP on addition of co-chaperones and CFP-IRE1 LD. The attachment of YFP had no effect on BiP basal activity, or stimulation by co-chaperones, or inhibition by CFP tagged IRE1 LD. Statistics as in Fig. 1, source data available online.

Source data

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