Extended Data Fig. 4: H3.3 enrichment within parental alleles in zygotes and 2-cell embryos.
From: Reprogramming of the histone H3.3 landscape in the early mouse embryo
a, Scatter plots showing normalized H3.3 enrichment in the maternal or paternal allele in zygotes (left) or 2-cell embryos (right). Bin size = 500 kb. b, Scatter plots showing the correlation between H3.3 enrichment in the maternal (left) or paternal (right) allele and H3K4me3 in 2-cell embryos. c, Heatmaps showing normalized allelic H3.3, H3K4me3 and H3K27me3 enrichment data. Published histone modification data (GSE73952 and GSE97778)33,34 are used. The analyses were performed for 10-kb bins showing H3.3 enrichment either in zygotes (left) or 2-cell embryos (right). The data were sorted by H3.3 enrichment level on the maternal allele. Enrichment is shown as log2 ratios between ChIP and input.
