Extended Data Fig. 2: Changes in the proportion of crystallin isoforms during aging in wild-type and mutant mice.
From: Imbalances in the eye lens proteome are linked to cataract formation
Graphs show relative proportions of single crystallin isoforms, plotted against age, in the water-soluble or -insoluble fractions from whole lens extracts (C3HeB/FeJ (black squares), αA mutant (red circles), γD mutant (red triangles) and C57Bl/6 J (black squares), βA2 mutant (red circles)). Data are shown as mean and s.d. for n = 2 individual animals. Data behind graphs are in Supplementary Data 1. The sum of the isoform proportions equals 1 and the analyses were performed for the water-soluble and water-insoluble fraction.
