Extended Data Fig. 7: Fits of complete EC* in representative densities.
From: Structure of complete Pol II–DSIF–PAF–SPT6 transcription complex reveals RTF1 allosteric activation
a, Fit of complete EC*-RTF1 in composite map used for refinement. Side, back and top views are shown as in Fig. 2. b, Complete EC* active site modelled in composite map used for refinement. Pol II active site is not altered upon RTF1 binding. Active site adopts post-translocated conformation. c, Fit of RTF1 helices and latch in local resolution filtered version of Map 2. d, RTF1 latch contacts with the RPB1 bridge helix and funnel helices in local resolution filtered version of Map 2. e, Fit of improved CTR9, WDR61, PAF1, and CDC73 model in Map 4. f, Fit of improved CTR9, WDR61, PAF1, and CDC73 model in Map 6. g, Fit of improved CTR9, WDR61, PAF1, and CDC73 model into previous CTR9 middle map H10.
