Extended Data Fig. 5: Cryo-EM of the H11-H4–Spike complex.
From: Neutralizing nanobodies bind SARS-CoV-2 spike RBD and block interaction with ACE2
(a) Unbiased 2D class averages of the complex. (b) 2D class averages selected for further processing. (c) FSC resolution criteria. (d) Particle orientation distribution for the final map showed no preferred orientation. (e) Final map colored according to local resolution. (f) Ribbon diagram of the complex and map (gray) contoured at 4 σ Chimera49. (g–i) The three H11-H4 nanobodies with map contoured at 4 σ Chimera49. Maps in f-i used amplitudes scaled based on the refined coordinates using LocScale63.
