Extended Data Fig. 3: Neutralization of live virus at Public Health England.
From: Neutralizing nanobodies bind SARS-CoV-2 spike RBD and block interaction with ACE2
The percentage reduction in plaques arising from virus is plotted againt increasing (left to right) concentration of (a) H11-H4-Fc (6 nM, 95 % CI 3–9 nM) (b) H11-D4-Fc (18 nM, 95 % CI 9–68 nM). The confidence intervals are shown as dashed lines. In Figure 3d,e 5d % infectivity (% infectivity = 100 - % plaque reduction) is plotted against decreasing (left to right) concetration of the agent. (c) The experimental plate with the codes noted below. The plaques caused by the virus are visible.
