Extended Data Fig. 9: Loops with an interwound DNA structure at the stem of loop.
From: The condensin holocomplex cycles dynamically between open and collapsed states
a, Example of an interwound DNA loop. Two arrows indicate the starting and ending points of an interwound DNA region. Yellow arrow indicates a condensin complex located near the loop stem. b, Fraction of loops with an interwound region at the stem (N = 116 molecules from 3 independent experiments). c, Scatter diagram of the protein width vs the neck size of normal (non-interwound) DNA loops (N = 88 loops). d, Idem for DNA interwound loops at the stem (N = 27 loops). A neck size of ~9 nm is observed, which may be attributed to the two parallel DNA molecules (that feature a ~2 + 2 nm dsDNA width), convoluted by the AFM tip size.
