Extended Data Fig. 5: WT ELOVL7 activity.
From: The structural basis of fatty acid elongation by the ELOVL elongases
a,b Activity of residual WT enzyme on incubation with stearoyl-CoA (C18:0) and malonyl-CoA. Selected ion recording is shown for a, reaction mixture without added enzyme and b, reaction mixture after 3hr incubation with ELOVL7 enzyme. The ion peak at 1.61 mins corresponds to the expected 3-keto-eicosanoyl (C20)-CoA product of the elongation reaction. This experiment was carried out with two biological repeats with similar results.
