Extended Data Fig. 10: Conformational changes accompanying temperature-induced opening of wild-type TRPV3. | Nature Structural & Molecular Biology

Extended Data Fig. 10: Conformational changes accompanying temperature-induced opening of wild-type TRPV3.

From: Structural mechanism of heat-induced opening of a temperature-sensitive TRP channel

Extended Data Fig. 10

Superposition of the closed- and heat-activated open-state structures of TRPV3 (cNW11, 42 °C) viewed parallel to the membrane is shown in the centre. Insets show select regions with the arrows indicating the displacement of domains in the open relative to the closed state. The lipid at the vanilloid site is shown in sticks (pink).

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