Extended Data Fig. 6: Sequence features around the proximal and distal polyA sites.
From: Alternative polyadenylation by sequential activation of distal and proximal PolyA sites
a, Enrichment score (log2[frequency in PAS / frequency in random sequence]) for AAUAAA, UGUA, and GU/U-rich motifs around the cleavage sites (±100 nt) of all polyA sites. b, Nucleotide frequency around (±100 nt) pPAS and dPAS in 4 different groups as in Fig. 3c. c, Distribution of U-rich 6-mer motifs (described in the Methods) in the region −100–0 nt upstream of the pPAS (blue) and dPAS (yellow) from 4 different groups.
