Extended Data Fig. 6: Cryo-EM density of bison NHA2 ΔN in nanodiscs.
From: Structure, mechanism and lipid-mediated remodeling of the mammalian Na+/H+ exchanger NHA2
Cryo-EM density map of the NHA2ΔN helices in nanodiscs. The respective helices are shown in cartoon representation for the 6-TM core transport (pink), the dimer domain (green), the N-terminal domain-swapped helix TM –1 (blue), with their cryo-EM map density in blue mesh. Density for several lipids is also shown in blue mesh, and modeled lipids as sticks with CHS (yellow), PI-headgroup (green) and PI tail (gray); other lipids and map density is shown in Extended Data Fig. 7c.
