Extended Data Fig. 1: CryoEM of intact V-ATPase.
From: Coordinated conformational changes in the V1 complex during V-ATPase reversible dissociation

a, Example micrograph (from a dataset of 4015 micrographs) and 2D class average images. b, Fourier shell correlation curves after gold-standard refinement and correction for masking for the three rotational states of intact V-ATPase. c, Local resolution maps and orientation distribution plots for rotational State 1 (top), State 2 (middle), and State 3 (bottom). d, Masks (light blue density) used for local refinement of the V1 region (top), subunit a and the collar region (middle), and the VO region (bottom) for V-ATPase (shown for State 1).