Extended Data Fig. 4: TLS inhibition does not enhance DSB formation during NEIL3-dependent ICL repair. | Nature Structural & Molecular Biology

Extended Data Fig. 4: TLS inhibition does not enhance DSB formation during NEIL3-dependent ICL repair.

From: The HMCES DNA-protein cross-link functions as an intermediate in DNA interstrand cross-link repair

Extended Data Fig. 4

a, REV1 and HMCES immunodepletion. The extracts used in the replication reactions shown in b were blotted for REV1 and HMCES. Asterisks, non-specific bands. b, pICLAP was replicated with [α-32P]dATP in the indicated extracts (shown in a). Replication intermediates were analyzed as in Fig. 2a.

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