Extended Data Fig. 7: Seeded aggregation of KRT8 by preformed recombinant KRT8 aggregates. | Nature Structural & Molecular Biology

Extended Data Fig. 7: Seeded aggregation of KRT8 by preformed recombinant KRT8 aggregates.

From: Identifying amyloid-related diseases by mapping mutations in low-complexity protein domains to pathologies

Extended Data Fig. 7

Pre-aggregated KRT81-90 was added to monomeric KRT81-90 (100 µM) and allowed to aggregate. The addition of pre-aggregated KRT8 enhances the aggregation of monomeric protein, presumably through template seeding. Experiment performed with n = 3 replicates. Error bars represent ± SD. Data for graphs is available as source data.

Source data

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