Extended Data Fig. 10: Condensin binding is length and supercoiling dependent.
(a) Observation probability of condensin on nicked DNA with two different lengths (21 kb and 48.5 kb), estimated by summing the total number of detected condensin peaks over all time points, and dividing this by the DNA length and measurement time. N = 8 molecules for 21 kb, N = 22 molecules for 48 kb length, respectively. (b) Condensin enrichment on supercoiled loops and relaxed loops, estimated by summing up the total intensity of the detected condensin peaks within the loop region with similar lengths (~60 % of its contour length). N = 25 molecules for supercoiled loops and N = 20 for relaxed loops, respectively. Data represent mean ± standard deviation.
