Extended Data Fig. 8: Density to model agreement.
From: Structure of the metastatic factor P-Rex1 reveals a two-layered autoinhibitory mechanism
a. Three rotated views of the cryo-EM reconstruction of ΔN40P-Rex1T4L,Δ1119-1211. Position of T4L is shown in purple. b. Select regions of high-resolution highlighting clear sidechain density c. Agreement between P-Rex1 model and cryo-EM density for each P-Rex1 domain. Regions of poor density due to anisotropy are shown with two views. Arrow indicates direction of the projection axis of the preferred orientation.
