Extended Data Fig. 3: SAXS analyses of H46 and H16.
From: The structure of pathogenic huntingtin exon 1 defines the bases of its aggregation propensity
The plots of average intensity vs. frame number obtained from SEC–SAXS for H16 (a) and H46 (b) The insets show all−vs-all χ2 comparison for the frames selected for further processing. The small values of χ2 show that the selected frames were very similar to each other. (c) Pairwise distance distribution functions, P(r), obtained for H16 (red) and H46 (blue) by indirect Fourier transformation of the SAXS data. (d) and (e) show the Rg distribution of the pool (gray, filled) and the selected sub-ensemble by EOM for H16 (red) and H46 (blue), respectively.
