Fig. 3: The cryo-EM structure of HsDis3L2 in complex with hairpinC–U12 shows engagement of the RNA duplex. | Nature Structural & Molecular Biology

Fig. 3: The cryo-EM structure of HsDis3L2 in complex with hairpinC–U12 shows engagement of the RNA duplex.

From: A shape-shifting nuclease unravels structured RNA

Fig. 3

a, RNA fold of hairpinC–U12. b, Wild-type Dis3L2 in complex with hairpinC–U12. c, View of b at 90°. d, Basal junction of the double-helical stem and overhang. e, Overlay of the map and structure showing the position of the double-helical stem of hairpinC–U12.

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