Extended Data Fig. 1: Cryo-EM structure of RNA-free human Dis3L2. | Nature Structural & Molecular Biology

Extended Data Fig. 1: Cryo-EM structure of RNA-free human Dis3L2.

From: A shape-shifting nuclease unravels structured RNA

Extended Data Fig. 1

a, Final 3D map of human Dis3L2 (left) with b, Gold Standard (0.143) Fourier Shell Correlation (GSFSC) and c, viewing direction distribution (bottom right). The 3D map was produced by homogeneous refinement of roughly 163-thousand particles in CryoSPARC. d, Surface representation and cut-away (right) showing the tunnel and the active site.

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