Extended Data Fig. 5: SNX1BAR domain enhances the interaction between the PX domain of SNX5 and CI-MPR. | Nature Structural & Molecular Biology

Extended Data Fig. 5: SNX1BAR domain enhances the interaction between the PX domain of SNX5 and CI-MPR.

From: Architecture of the ESCPE-1 membrane coat

Extended Data Fig. 5

Representative ITC experiments for the binding of the cytosolic region of CI-MPR (amino acids 2330-2491) (panels b, c), or the bipartite sorting motif (amino acids 2347-2375) (panels a, d-i) titrated into ESCPE-1 or selected subdomains. Top panels show the raw data and bottom panels represent the integrated and normalized data fit with a 1:1 binding model. Data are representative of at least two independent experiments.

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