Extended Data Fig. 2: AGO2 localization in quiescent versus proliferating cells.
From: AGO2 silences mobile transposons in the nucleus of quiescent cells

(a) Ex-vivo splenocyte activation leads to a significant increase in cell size. (b) Splenocyte activation has minimal impact in relative sizes of nuclear and cytoplasmic compartments. (c) Percentage of total HA signal that is localized to the nucleus in activated B and T splenocytes. (d) Percentage of total HA signal that is localized to the nucleus in primary MEFs grown in complete media (10% serum; Fed), serum starved for 8 days (0.1% serum; Starved, Str), and refed for 24 h following an 8-day serum starvation (Refed, Ref). For all boxplots, each dot represents a cell. Boxplots show minimum, maximum, median, first, and third quartiles. Median value (x) and number (n) of cells analyzed per condition are shown. Values are based on 93 resting and 154 activated B cells or 141 resting and 69 activated T cells collected from two independent experiments. P values were calculated with a two-sided Wilcoxon test.