Extended Data Fig. 1: Sequence alignment of mouse MATER and human MATER. | Nature Structural & Molecular Biology

Extended Data Fig. 1: Sequence alignment of mouse MATER and human MATER.

From: Structural basis of the subcortical maternal complex and its implications in reproductive disorders

Extended Data Fig. 1

Mouse MATER lacks the N terminal PYD domain lacks the N terminal repeat (black box outlined). The PYD domain of human MATER was outlined with the green box. The β-strand 7 was essential for binding with FLOPED. The residues of CTL (W1046, Y1047, D1053) in contact with LRR (R843, D930, S985) were conserved in human MATER.

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