Extended Data Fig. 5: Chemical cross-linking mass spectrometry (XL-MS) analysis of the KBTBD2–p85α complex.
From: Dynamic molecular architecture and substrate recruitment of cullin3–RING E3 ligase CRL3KBTBD2
a, The circular plot of cross-links identified for the KBTBD2-p85α complex. b, KBTBD2–p85α inter- (blue) and intra-subunit (orange) cross-links projected onto the cryo-EM structure of CRL3KBTBD2–p85α. c, Euclidean distances for cross-links shown in (a). d-e, Cryo-EM density maps of CRL3KBTBD2–p85α dimer fitted with the corresponding models of KBTBD2 and p85α. The domains are labeled in different colors.
