Extended Data Fig. 6: Intramolecular interaction of preS1.
From: Structural basis of hepatitis B virus receptor binding
a, Cross-sectional views of human NTCP in complex with myr-preS1 (top). PreS1 is shown as a ribbon model. PreS1 is colored from blue to yellow, from the N- to C-terminus. Side chains of the residues involved in intramolecular interactions are displayed as stick representations. Red dashed line, salt bridge; black dashed line, hydrogen bond. Close-up views of the anti-parallel β-strand (residues 3–5 and 32–34) (bottom left) and two pairs of salt bridges (K24–D31 and D33–K38) (bottom right). b, List of residues involved in the intermolecular hydrogen bonds between preS1 and human NTCP.
