Extended Data Fig. 5: Structural comparison of the human U5 snRNP to the yeast Prp8-Aar2 structure.
From: Structural basis of human U5 snRNP late biogenesis and recycling
a. Comparison of PRP8L domains in the human U5 snRNP (State I, left) and the yeast Saccharomyces cerevisiae Prp8-Aar2 crystal structures24 (PDB ID 4I43, right). The PRP8 α-finger is highlighted with a black outline. Colors as in Fig. 1; Aar2 (light pink). b. Comparison of PRP8 α-finger conformations in the human U5 snRNP (State I, left) and the yeast Prp8-Aar2 crystal structures24 (PDB ID 4I43, right).
