Extended Data Fig. 9: Assembly competency of O432-17(-) trimer variants.
From: Computational design of non-porous pH-responsive antibody nanoparticles
a, SEC elution profile of the trimer component on a Superdex 200 GL 10/300 chromatography column. b, SEC elution profile of the full O432-17 assembly containing each trimer variant assembled with tetramer and Fc and purified on a Superose 6 GL 10/300 chromatography column. c, DLS profile of the resulting assembly as normalized intensity. d, Representative nsEM and reference-free two-dimensional class averages of each assembly variant. Scale bar 100 nm and 10 nm, respectively.
