Extended Data Fig. 2: Dose-response curves of Different Southern Hemisphere Analogs.

Responses of Sm.TRPMPZQ to the molecules are shown in blue circles, Fh.TRPMPZQ in red circles, and control (untransfected cells) red diamonds. All data are presented as mean ± SEM. N = 3 biological replicates comprised of technical duplicates except for the following: untransfected cells, technical duplicates; compound 27, Fh.TRPMPZQ, n = 4 biological replicates comprised of technical duplicates; compound 30, Sm.TRPMPZQ, n = 9 biological replicates comprised of technical duplicates.