Extended Data Fig. 5: Structured lipids stabilize the AMPAR TMD. | Nature Structural & Molecular Biology

Extended Data Fig. 5: Structured lipids stabilize the AMPAR TMD.

From: Allosteric competition and inhibition in AMPA receptors

Extended Data Fig. 5

Coulomb potential maps of the AMPAR TMD from signal subtraction and focused refinement highlighting the presence of lipids (blue) bound to the TMD. (i) close-up of lipids bound to the B/D TMD subunits of the receptor showing at least seven distinct densities. (ii) close-up of the A/C subunits of the receptor demonstrating similar, but distinct lipid arrangements around the TMD.

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