Table 1 Individual cell mean residual current, s.d. and number of sweeps for each GYKI-54266 concentration, along with the initial response in the absence of GYKI-52466
From: Allosteric competition and inhibition in AMPA receptors
[GYKI-52466] (µM) | Mean residual current from Glu + CTZ + GYKI-52466 (pA) | s.d. (pA) | Number of sweeps | Initial mean residual current from Glu + CTZ (pA) | s.d. (pA) | Number of sweeps |
|---|---|---|---|---|---|---|
1 | −3,133.63 | 39.85 | 3 | −3,209.37 | 21.95 | 2 |
−169.22 | 5.39 | 4 | −185.05 | 4.09 | 6 | |
−1,561.56 | 19.94 | 3 | −1,619.52 | 17.08 | 4 | |
−240.30 | 7.91 | 6 | −261.97 | 5.12 | 4 | |
3 | −31.87 | 1.47 | 4 | −37.72 | 1.31 | 6 |
−8,108.75 | 104.25 | 3 | −9,585.67 | 49.35 | 2 | |
−229.67 | 5.10 | 4 | −247.38 | 5.30 | 5 | |
−152.64 | 6.44 | 5 | −169.66 | 5.52 | 4 | |
10 | −2,778.95 | 65.47 | 2 | −3,209.37 | 21.95 | 2 |
−143.85 | 6.19 | 3 | −185.05 | 4.09 | 6 | |
−1,790.07 | 60.42 | 3 | −2,371.98 | 40.00 | 5 | |
−230.18 | 6.20 | 4 | −265.72 | 7.21 | 3 | |
30 | −18.86 | 2.09 | 5 | −37.72 | 1.31 | 6 |
−5,705.77 | 158.82 | 3 | −9,585.67 | 49.35 | 2 | |
−174.54 | 7.78 | 3 | −247.38 | 5.30 | 5 | |
−100.41 | 4.54 | 4 | −169.66 | 5.52 | 4 | |
100 | −798.20 | 39.99 | 3 | −3,209.37 | 21.95 | 2 |
−66.33 | 4.17 | 3 | −185.05 | 4.09 | 6 | |
−390.00 | 25.57 | 3 | −2,371.98 | 40.00 | 5 | |
−34.70 | 3.65 | 4 | −265.72 | 7.21 | 3 | |
300 | −1.41 | 0.60 | 4 | −37.72 | 1.31 | 6 |
−385.81 | 14.45 | 4 | −9,585.67 | 49.35 | 2 | |
−41.93 | 3.72 | 2 | −247.38 | 5.30 | 5 | |
−7.56 | 1.31 | 5 | −169.66 | 5.52 | 4 | |
−16.67 | 1.97 | 10 | −131.32 | 2.01 | 6 |
