Extended Data Fig. 9: Comparison between observed and full-length predicted ωRNA architecture.
From: Structure of Fanzor2 reveals insights into the evolution of the TnpB superfamily
a. Atomic model of ωRNA scaffold (including nucleotides -205 to -152, -79 to -77, -65 to -38, -18 to 13). Black dashed curve represents unresolved multi-stem branching from Stem2. b-c. Structure of predicted full-length ωRNA (top) and observed ωRNA (bottom). Only ωRNA is shown in b, whereas protein and ωRNA are shown in c. The predicted ωRNA structure was generated by docking RNAcomposer predictions of the individual RNA stem loops onto the final cryo-EM model. Disordered regions are displayed in a dashed grey box. Rotations relative to a (top) are indicated. Top and bottom panels in b and c depict the same viewing direction.
