Extended Data Fig. 4: Cryo-EM density and associated model of representative parts of the closed and open CtMrs2 states. | Nature Structural & Molecular Biology

Extended Data Fig. 4: Cryo-EM density and associated model of representative parts of the closed and open CtMrs2 states.

From: Closed and open structures of the eukaryotic magnesium channel Mrs2 reveal the auto-ligand-gating regulation mechanism

Extended Data Fig. 4

a, The closed CtMrs2 pentamer, a separate monomer, and different segments. The cardiolipin density is colored in yellow. b, The open CtMrs2 pentamer, a separate monomer, and different segments. Interestingly, the open structure displays a clear lipid feature density in the groove between TM1 and TM2 of two adjacent monomers.

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