Extended Data Fig. 1: Functional characterization and secondary structure of CtMrs2. | Nature Structural & Molecular Biology

Extended Data Fig. 1: Functional characterization and secondary structure of CtMrs2.

From: Closed and open structures of the eukaryotic magnesium channel Mrs2 reveal the auto-ligand-gating regulation mechanism

Extended Data Fig. 1

a, Growth comparison of wild-type and Mrs2 knockout S. cerevisiae on fermentable carbon source (with glucose) and nonfermentable carbon source (glycerol). b, Live cell bioimaging micrographs of yeast cells expressing CtMrs2 with bright light (left) and GFP fluorescence (right), The scale bar represents 5 µm. The experiments were performed more than five times independently. The protein likely partitions to mitochondria. c, Schematic depiction of the secondary structure of a CtMrs2 monomer. d, Cartoon representation of the CtMrs2 monomer, colored as in panel c. e, Surface electrostatics of CtMrs2 with close-views of the basic and acidic rings.

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