Extended Data Fig. 7: Sequence alignment of Vesicular Acetylcholine Transporter homologues.
From: Binding mechanism and antagonism of the vesicular acetylcholine transporter VAChT
Sequence alignment among human VAChT (hVAChT), human VMAT1 (hVMAT1), human VMAT2 (hVMAT2), Mus musculus VAChT (mVAChT), Rattus norvegicus VAChT (rVAChT), Drosophila melanogaster VAChT (dVAChT), Tetronarce californica VAChT (tcVAChT), and Torpedo torpedo VAChT (ttVAChT). The secondary structural elements of hVAChT are depicted above the sequence alignment, with unmodeled regions represented as dashed lines and transmembrane domains represented as grey rectangle boxes. Conserved acidic, basic, and other types of amino acid residues in the protein are highlighted using red, blue, and grey, respectively.
