Extended Data Fig. 2: THIK1EM:MSP1E1 nanodisc (ND) cryo-EM map and model quality. | Nature Structural & Molecular Biology

Extended Data Fig. 2: THIK1EM:MSP1E1 nanodisc (ND) cryo-EM map and model quality.

From: Structure of the human K2P13.1 channel reveals a hydrophilic pore restriction and lipid cofactor site

Extended Data Fig. 2

a, Cryo-EM map of the THIK1EM:ND complex. THIK1EM and associated lipids are colored magenta and turquoise. Locations of select channel elements are indicated. Nanodisc density is transparent. b, Cryo-EM maps for indicated THIK1EM elements. Select residues are indicated. Channel elements are deep salmon. Linoleic acid (EIC) is yelloworange. Maps are rendered at 4-5σ. c, THIK1EM:ND local resolution. Select channel elements and lipid belt are labeled. d, THIK1EM:ND local B-factor.

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