Fig. 3: Fascin’s two F-actin binding interfaces are chemically distinct.
From: Fascin structural plasticity mediates flexible actin bundle construction
a, Overview of fascin’s two F-actin binding interfaces. b, Contacts between subdomain 1 (SD1) of actin subunit i + 2 and fascin β1. c, Contacts between SD1 of actin subunit i, D-loop of subunit i + 2 and fascin β1. Protein kinase C target residue S39 of fascin is highlighted in space-filling representation. d, Contacts between SD1 of actin subunit i and fascin β4. e, Contacts between SD1 of actin subunit j + 2 and fascin β2, including cation clustering interaction between fascin R149 and actin R28. f, Contacts between SD1 of actin subunit j, D-loop of subunit j + 2 and fascin β3.
