Extended Data Fig. 4: The incomplete maps lack density for the CTD but are otherwise similar to the complete map. | Nature Structural & Molecular Biology

Extended Data Fig. 4: The incomplete maps lack density for the CTD but are otherwise similar to the complete map.

From: Initiation of ERAD by the bifunctional complex of Mnl1/Htm1 mannosidase and protein disulfide isomerase

Extended Data Fig. 4

(a) The model derived from the complete map was docked into the Incomplete #1 density map. The interaction between Mnl1 (in purple) and Trx a’ domain of Pdi1 is shown. Note the model fits well into the map. (b) As in (a), but for the interaction between Mnl1 and the Trx a domain of Pdi1. (c) As in (a), but for the active site of the MHD domain of Mnl1. The Ca2+ ion is shown in green. (d) The left panel shows an overlay of the density map of Incomplete #1 (shown as surface, blue) with that of Incomplete #2 (shown as mesh, orange). The right panel shows an overlay of the density map of Incomplete #1 with that of Incomplete #3 (shown as mesh, yellow).

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