Centrosomal protein assemblies can lead to mitotic spindle dysfunction and abnormal cell division. Two studies published in this issue unveil the molecular choreography orchestrated by TRIM37 in blocking the accumulation of these structures in a remarkable fashion that resembles viral capsid recognition.
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Work in the Basto lab is supported by the CNRS and Institut Curie.
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Basto, R. TRIMming centrosomal assemblies. Nat Struct Mol Biol 32, 1589–1590 (2025). https://doi.org/10.1038/s41594-025-01549-x
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DOI: https://doi.org/10.1038/s41594-025-01549-x
