Fig. 5: ULK1 dimerization on the FIP200 scaffold.
From: Structure and activation of the human autophagy-initiating ULK1C:PI3KC3-C1 supercomplex
a, Representative 2D class average and the EM map of the ULK1C (2:2:2) core in the presence of PI3KC3-C1. The ULK1MIT:ATG13MIM domains are indicated with arrows. Scale bar, 20 nm. The EM map is contoured at 7σ. b, Representative 2D class average and EM map of the ULK1C (2:2:2) core of the ATG13450–517 truncation mutant. The EM map is contoured at 14σ. c, Repeated 2D class averages and EM map of the ULK1C (2:1:1) core as shown in Fig. 1b,c for comparison. The EM map is contoured at 12σ.
