Extended Data Fig. 4: Autoinhibitory activity of various Sgt2 constructs.
From: Remote on–off switching of protein activity by intrinsically disordered region
a-c, Amino acid sequences of domains used for Sgt2T replacement: GB1 (a), TRX (b), and SgtAT with sequence alignment to Sgt2T (c). d-g, Disordered sequences replacing Sgt2C tail: 65-residue Tau fragment (d), scrambled Sgt2C (e), 20-residue disordered L20 sequence (f), and C-terminal tail from homolog SgtA (SgtAC) (f), with sequence alignment (g).
